At Self Aesthetics, we’re proud to offer some of the most advanced regenerative skin treatments available today. One of the most exciting breakthroughs in natural aesthetic medicine is Platelet-Rich Fibrin (PRF) — a next-generation therapy that uses your own blood to promote collagen, elastin, and long-term skin rejuvenation.
More than just a beauty treatment, PRF offers science-backed benefits for skin texture, tone, and firmness — with no synthetic ingredients, no additives, and no downtime.
In this blog, we’ll explore the benefits of PRF, how it compares to PRP and Biofiller, and what you can expect from the treatment journey, including insights from the Alocuro PRF system used at Self Aesthetics.
What Is PRF and How Does It Work?
Platelet-Rich Fibrin (PRF) is a 100% autologous (from your own body) injectable concentrate that contains high levels of:
- Platelets
- Leukocytes (white blood cells)
- Mesenchymal stem cells
- Fibrin scaffold
- Cytokines and exosomes
- Regenerative growth factors
Unlike PRP (Platelet-Rich Plasma), which requires anticoagulants and is processed at high speeds, PRF is prepared using a slow centrifugation protocol that allows for more stem cells and platelets to be preserved. The result is a fibrin matrix that acts as a scaffold, slowly releasing growth factors over a period of 7–10 days, offering extended regenerative support to the skin.
At Self Aesthetics, we use the Alocuro PRF system, a closed, sterile system designed to optimise the quality of the PRF concentrate. Alocuro’s clinical research confirms that PRF provides higher concentrations of growth factors such as PDGF, TGF-β, VEGF, and IGF compared to PRP alone — all of which are essential for tissue regeneration, collagen production, and skin remodelling.
Key Benefits of PRF for Facial Rejuvenation
PRF has quickly become a favourite among patients looking for natural, regenerative skin treatments that offer visible results without harsh chemicals or synthetic fillers.
1. Stimulates Natural Collagen and Elastin
The slow release of growth factors enhances fibroblast activity, promoting the production of new collagen and elastin, which improves skin texture and firmness over time.
2. Restores Volume and Hydration
The fibrin matrix adds subtle volume in delicate areas like the tear trough, smile lines, and lip borders, while also attracting moisture for improved plumpness.
3. Brightens Skin Tone
PRF improves microcirculation and reduces inflammation, which helps reduce pigmentation, dullness, and signs of fatigue.
4. Reduces Fine Lines and Wrinkles
Through collagen remodelling, PRF softens the appearance of static lines and creases, particularly around the eyes, mouth, and nasolabial folds.
5. Supports Fat and Muscle Preservation
Regular PRF treatments help maintain the integrity of facial fat pads and underlying muscle tone, which play a critical role in youthful facial structure.
PRF vs PRP vs Biofiller: What’s the Difference?
| Feature | PRP | PRF | Biofiller |
| Processing | Fast centrifuge with additives | Slow centrifuge, no additives | Heat-treated PRF (gel consistency) |
| Composition | Platelets only | Platelets + WBCs + stem cells | Gelled PRF for volume replacement |
| Longevity | Short-term effect (24–48 hrs) | Slow release (7–10 days) | Temporary filler-like effect |
| Best For | Texture and healing | Volume + regeneration | Soft volume replacement |
PRP is best for improving surface skin texture and glow, while PRF excels in both surface renewal and structural support. Biofiller (heated PRF turned into a gel) offers a natural filler alternative for clients who want volumisation without synthetic HA fillers.
At Self Aesthetics, we often combine all three based on your ageing pattern, skin quality, and aesthetic goals.
The In-Clinic Process: What to Expect
- Blood Collection: A small sample of your blood is drawn in our clinic using a sterile Alocuro PRF tube.
- Centrifugation: The sample is spun at a low G-force using the Alocuro PRF system for 8–12 minutes.
- Injection: The PRF is injected into target areas such as the tear trough, nasolabial folds, marionette lines, and perioral area.
- Skin Needling (optional): For full-face rejuvenation, PRF is often combined with microneedling to boost collagen production and improve skin penetration.
When Will I See Results?
Most patients begin to notice improvement in skin texture and hydration within 2–3 weeks after treatment. Volume support and wrinkle reduction become more evident over the next 4–6 weeks, as collagen remodelling takes place.
Results are subtle and natural — and because PRF improves the health of your skin at a cellular level, the effects are progressive and long-lasting.
How Many Treatments Are Needed
For optimal rejuvenation, we recommend a series of 3 treatments spaced 6 weeks apart, followed by maintenance every 4–6 months. This schedule ensures continued activation of your skin’s regenerative pathway.
Exclusive Offer at Self Aesthetics
Pre-purchase 3 PRF treatments and receive your 4th treatment FREE.
Anti-Aging Indications Treated with PRF
PRF can effectively address:
- Tear trough hollowing
- Fine lines and wrinkles
- Volume loss in smile lines
- Lip border definition
- Skin laxity
- Uneven skin tone or dullness
- Mild acne scarring
- Collagen loss due to ageing or sun damage
Aftercare and Immediate Post-Treatment Expectations
After PRF treatment, you may experience:
- Mild swelling or puffiness at injection sites (especially under the eyes)
- Pinpoint bruising that resolves within a few days
- Warmth or tightness in the treated area (a sign of increased blood flow)
- No downtime, although avoiding strenuous activity and active skincare for 24–48 hours is advised
Aftercare Tips:
- Avoid touching or massaging the area for 24 hours
- Use gentle, non-active skincare
- Stay hydrated and avoid alcohol
- Avoid saunas, steam rooms, and direct sun exposure for 48 hours
Why PRF Is a Long-Term Skin Investment
Unlike one-off cosmetic procedures that fade over time, PRF builds healthier skin over the long term. By stimulating your body’s own healing and collagen production mechanisms, you preserve your natural beauty, prevent future volume loss, and delay the visible signs of ageing.
Whether used alone or in combination with PRP, microneedling, or biofiller, PRF offers one of the most biologically intelligent anti-ageing treatments available today.
Book your PRF consultation at Self Aesthetics today
And start the journey toward luminous, lifted, and naturally rejuvenated skin.
